Ingredients for Products
Cosmetic ingredients
Ranman lees extract
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Product name
Ranman lees extract Plant BG version (general cosmetic raw material)
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Quantity
1kg
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１．Induction of HSP60 expression in lees
HSP60 is a member of the chaperonin family and is an important protein for protein folding, and decreases with age.
The lees extract was freeze-dried, added to CACO-2 cells at a concentration of 0.1 mg / ml in the medium, and cultured for 12 hours. As a result, the expression level of HSP60 increased.
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２．Anti-aging effect of lees
Thymidine is known as an aging inducer.Caco-2 to which lees were added and Caco-2 to which no lees were added were cultured in advance, and Thymidine was added to continue the culture.Caco-2 with lees added continued cell proliferation longer than without lees.
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３．Anti-Doxorubicin aging induction by lees
Doxorubicin (DXR)：It is an anticancer drug and is also used to induce aging.
The cell proliferation inhibitory effect was alleviated by the lees.
